Antithyroid substances. 3. Derivatives of 2-mercaptoglyoxalines
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چکیده
منابع مشابه
Synthesis and Antithyroid Activity of Some 8-Substituted Purine Derivatives
Some novel as well as known derivatives of 8-sulfanyl-3,9dihydro-1H-purine-2,6-dione were synthesized and their antithyroid activity was measured in rats after administration of a daily dose of 20mg/kg via i.p. injection for 15 days. Free thyroxine and triiodothyronine concentrations were determined using radioimmunoassay technique. The assay results showed decrease in the hormonal concentratio...
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It was first shown by Heim et al. (2, 3) that 1 hour after S-amino-l ,2,4-triazolel has been injected into rats, there is a marked inhibition of liver and kidney catalase, a lesser inhibition of liver peroxidase, and no inhibition of erythrocyte catalase activity. In view of this rather selective action towards tissue hydroperosidases, it seemed possible that aminotriazole should exhibit antith...
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The assessment of the degree or rate of cellular proliferation and cell viability is critical for the assessment of the effects of drugs on both normal and malignant cell populations. In the present study, a few novel 3-substituted derivatives of 2-indolinones were synthesized by condensation of substituted oxindole or isatin derivatives with appropriate aldehydes or primary aromatic amine...
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The assessment of the degree or rate of cellular proliferation and cell viability is critical for the assessment of the effects of drugs on both normal and malignant cell populations. In the present study, a few novel 3-substituted derivatives of 2-indolinones were synthesized by condensation of substituted oxindole or isatin derivatives with appropriate aldehydes or primary aromatic amine...
متن کاملPreparation and NMR, Mass and Mössbauer Studies of Di-and Triorganotin (IV) Derivatives of 3-(2-Furanyl)-2- Propenoic Acid
3-(2-Furanyl)-2-propenoic acid has been used to prepare a new series of organotin complexes of general formula R3SnL (R=Me, Et, n-Bu, Ph and Cy) and R2SnL2 (R=Me and n-Bu). These complexes have been characterized by elemental analyses, IR, 1H-NMR, MASS and Mössbaure spectroscopy.
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1955
ISSN: 0306-3283
DOI: 10.1042/bj0590345